(3aR,6aS)-5-Oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid 1,1-dimethylethyl ester - Names and Identifiers
(3aR,6aS)-5-Oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid 1,1-dimethylethyl ester - Physico-chemical Properties
Molecular Formula | C12H19NO3
|
Molar Mass | 225.28 |
Density | 1.139±0.06 g/cm3(Predicted) |
Boling Point | 325.8±35.0 °C(Predicted) |
pKa | -0.82±0.20(Predicted) |
Storage Condition | 2-8°C |
Sensitive | Irritant |
MDL | MFCD11616063 |
(3aR,6aS)-5-Oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid 1,1-dimethylethyl ester - Introduction
cis-5-Oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid tert-butyl ester (abbreviated as DIBOC) is an organic compound. It is a white crystalline solid with a low melting and boiling point.
DIBOC is widely used as a protecting group in organic synthesis to protect hydroxyl groups (such as alcohols and phenols) to prevent unnecessary reactions. It can form a stable Ester structure by reacting with the hydroxyl group, and the original hydroxyl group can be restored by the reaction of the protective agent when necessary.
The method of preparing DIBOC is usually by reacting carboxylic acid with tosyl chloride (TsCl) to obtain a carboxylic acid sulfonyl Ester, and then reacting it with tert-butyl alcohol to form DIBOC.
Regarding safety information, DIBOC is a chemical and needs to be handled with care. It can cause irritation to the skin and eyes. Appropriate personal protective measures should be taken during use, such as wearing gloves and goggles. In addition, during storage and handling, it is necessary to keep away from ignition and oxidizing agents to avoid fire or explosion accidents.
Last Update:2024-04-09 20:52:54